Validation of a Spectrophotometric Method of Some Antidepressant Drugs

Abstract Although the causes of depression include a wide range conditions, from neurodegenerative to thyroid, they all have one common denominator, changes in brain. Depression can be located multiple brain regions simultaneously, which may derived molecular abnormality found neurons many regions. Abnormalities receptors or impulse transmission could answer. In this work, simple and accurate spectrophotometric method was developed for analysis escitalopram oxalate various pharmaceutical formulations. method, absorbance measured at 238 nm oxalate. Method validation parameters were studied. The used quality control forms containing escitalopram. Also, by same actual active substance concentrations compared those listed on package, standard deviations relative deviations.